From November 14 to 17, Chinese PLA General Hospital, together with MIT, Harvard Medical School, Institute of Data Science of Tsinghua University, Society of Critical Care Medicine of Beijing Academy of Physiological Sciences etc. jointly held “The 4th PLAGH-MIT Critical Data Conference and Datathon” in Beijing. Through academic exchanges, forum interaction, roadshow competition, achievement demonstration, international leading experts from the field of medical big data and artificial intelligence comprehensively expounded the frontier and future development direction of medical big data and artificial intelligence technology from multiple perspectives, as well as explored open scientific research and interdisciplinary cooperation manner. This conference has attracted more than 500 people from all over the world in related fields.